Fig. 8. Vasodilator responses to the nitric oxide donor sodium nitroprusside (3 × 10−8, 3 × 10−7, and 3 × 10−6m) in the absence or presence of glibenclamide (5 × 10−6m) in rat cerebral parenchymal arterioles. Baseline diameters were 7.4 ± 2.3 and 7.1 ± 1.2 μm for control arterioles and arterioles treated with glibenclamide, respectively. Vasoconstrictor responses to prostaglandin F2α(5 × 10−7m) were 20.0 ± 11.7 and 22.7 ± 6.0% for control arterioles and arterioles treated with glibenclamide, respectively. Data are expressed as mean ± SD.
