Fig. 5. Effects of the two different adenosine triphosphate-sensitive K+channel blockers glibenclamide (Glib; 2 μm) and 5-hydroxydecanoate (5-HD; 300 μm) on attenuation of state 3 mitochondrial respiration by 1.3 mm sevoflurane (Sev) when substrates for complex I (10 mm pyruvate with 10 mm malate; A ) or for complex II (10 mm succinate with 10 μm rotenone; B ) were given. All values are mean ± SEM, n = 8 per experimental group. *P < 0.05 versus  Con. †P < 0.05 versus  sevoflurane (two-tailed).

Fig. 5. Effects of the two different adenosine triphosphate-sensitive K+channel blockers glibenclamide (Glib; 2 μm) and 5-hydroxydecanoate (5-HD; 300 μm) on attenuation of state 3 mitochondrial respiration by 1.3 mm sevoflurane (Sev) when substrates for complex I (10 mm pyruvate with 10 mm malate; A ) or for complex II (10 mm succinate with 10 μm rotenone; B ) were given. All values are mean ± SEM, n = 8 per experimental group. *P < 0.05 versus  Con. †P < 0.05 versus  sevoflurane (two-tailed).

Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal