Fig. 1. Time course of the antihypersensitivity effects of intrathecally administered T62 (left ) and clonidine (right ) in rats with 1 day after paw incision surgery. Presurgery baseline values are indicated at the time before 0. Withdrawal thresholds are expressed as mean ± SEM for seven or eight rats in each group. For T62, *P <0.05 versus vehicle (20% dimethyl sulfoxide) group, #P <0.05 versus 0.3 μg–treated group,+P <0.05 versus 0.5 μg–treated group. For clonidine, *P <0.05 versus 1 μg–treated group, #P <0.05 versus 3 μg–treated group.