Fig. 3. Concentration–response curves of the effects of anesthetics on tyrosine phosphorylation in rat hippocampal slices. Data (mean ± SD) are expressed as a fractional increase from basal phosphorylation (control = 100%). Western blots show the effects of anesthetic concentrations on total tyrosine phosphorylation ( upper panels ) and on specific focal adhesion kinase (pp125FAK) phosphorylation ( lower panels ). ** P < 0.05 versus control. ** P < 0.01 versus control. *** P < 0.001 versus control.