Fig. 7. Effects of dantrolene (50 μm) and U 73122 (30 μm) on anesthetic-induced tyrosine phosphorylation in rat hippocampal slices. Data (mean ± SD) are expressed as a fractional increase from basal phosphorylation (control = 100%). The anesthetic and pharmacologic agents were used at the following concentrations: desflurane, sevoflurane, and isoflurane: 0.3 mm; propofol, etomidate, and thiopental: 5 μm. *  P < 0.01 and **  P < 0.01  versus control. #  P < 0.05  versus anesthetic-induced tyrosine phosphorylation. NS = not significant.