![Fig. 5. The effects of sevoflurane (SEV) on the angiotensin II–elicited increase in intracellular Ca2+concentration ([Ca2+]i) in rat aortic smooth muscle. The endothelium-denuded rat aortic strips were treated with the fura-2 solution and were then exposed to 0 (control), 3.4, 5.1, or 8.5% sevoflurane for 15 min. The amount of fluorescence in the presence of angiotensin II (10−7m) was measured using a fluorometer. [Ca2+]iwas indicated as F340:F380 and was expressed as a percentage of the 30 mm KCl–elicited increase in [Ca2+]i(n = 7–9; control).](https://asa2.silverchair-cdn.com/asa2/content_public/journal/anesthesiology/100/4/10.1097_00000542-200404000-00018/2/18ff5.png?Expires=1716610128&Signature=tsxVQMHda68tKm~fsbvY-mmUnW4y5TOHT0rQtTiz07WWbvDYIYXftvMGgdY4BgmVa7vnUOKQjxIw2aN9N50mJ0acxx68sVVis6oPuzLz7vt8iCl89f~pJR24Q-pbNeIe59pLGpZLBh~ZK7iYEyocFRUo8smVHNKlBmm6JqjDxbNyrxoU1nsVP~l7cKY~sSWQQJXDYoY5WvYI3L41Dg6zWEs~xSSD-jbzpVimGKrplDLDegIaJ5HzpefUvg4fxVqPRWvV3GZuEbdEJPj1X97nu3NB3P4Gxuqvhz2A8wq26T9tuy7ldh6xuV56jOQBwx~w9bWNzLPUDEAXZZZTksJkFg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Fig. 5. The effects of sevoflurane (SEV) on the angiotensin II–elicited increase in intracellular Ca2+concentration ([Ca2+]i) in rat aortic smooth muscle. The endothelium-denuded rat aortic strips were treated with the fura-2 solution and were then exposed to 0 (control), 3.4, 5.1, or 8.5% sevoflurane for 15 min. The amount of fluorescence in the presence of angiotensin II (10−7m) was measured using a fluorometer. [Ca2+]iwas indicated as F340:F380 and was expressed as a percentage of the 30 mm KCl–elicited increase in [Ca2+]i(n = 7–9; control).
