Fig. 2. The effects of isoflurane on learning, memory, and pain sensitivity. ( A ) No significant effect on task acquisition was found. ( B ) A significant reduction in memory retention latency occurred with the 0.2% dose. A stronger amnesic effect was found with the 0.3% dose. ( C ) Analgesia was found at 0.2% and proportionally increased at 0.3%. The other details are as in figure 1 . * P < 0.05, *** P < 0.001 compared with air controls. NS = not significant.