Fig. 1. Magnetic resonance images of a 55-yr-old man with a gliosarcoma located in the right temporoparietal region. Diffusion-weighted imaging (DWI) sequences ( top row ) and apparent diffusion coefficient (ADC) maps ( middle row ) were obtained (1) on the day before surgery, (2) before and (3) 20 min after administration of indomethacin (bolus of 0.2 mg/kg followed by infusion of 0.2 mg · kg−1· h−1) in the propofol-fentanyl–anesthetized patient, and (4) 2 days after surgery. Fluid attenuated inversion recovery (FLAIR) sequences ( bottom row ) were performed (1) on the day before surgery and (2) 2 days after surgery. Despite considerable mass effect of the tumor, DWI and FLAIR images revealed no ischemic tissue damage. The finger-shaped surgical cavity appears black on DWI and white on ADC pictures in the last column (2 days after surgery). The area in the right frontal operculum just anterior to the surgical cavity, which appears white on DWI and black on ADC images, represents a small cortical lesion during the partial tumor resection .