Fig. 1. Schematic drawings of a 1-cm-long incision and suturing for behavioral experiments in which mechanical stimuli were applied to a primary area (an area adjacent to) (  A ) and a secondary area (an area distant from) (  B ) the incisional injury. Threshold of withdrawal in response to von Frey hair stimulation (  C, D ) and the scores of responses to brush stimulation (  E, F ) in the primary area and the secondary area after the incision. #  P < 0.01  versus preincision values; *  P < 0.05  versus preincision values.