Fig. 2. Representative left ventricular (LV) pressure (P)-volume (V) loops and end-systolic pressure-volume relations (dotted curves) during an aortic occlusion in ejecting in situ hearts without ( A and B ) and with brief ischemia and reperfusion (bIR) ( C and D ). ( A ) and ( C ) Prepropofol infusion (Pre). ( B ) and ( D ) 30-min propofol infusion at 40 mg·kg−1·h−1. Volume axes indicate normalized absolute LV volume for 1 g LV mass. Vo value was not subtracted from LV volume value .