Fig. 3. Most sensitive sites ( A ) and mean sizes ( B ) of receptive fields (RFs) of wide-dynamic-range (WDR) neurons located rostral and caudal to the spinal cord injury (SCI) lesion. The data of RF sizes were obtained from 22 rostral WDR neurons and 15 caudal WDR neurons in sham-operated animals and 25 rostral WDR neurons and 14 caudal WDR neurons in SCI animals. Representative responses of WDR neurons located rostral and caudal to the SCI site to nonnoxious and noxious stimuli in control (sham-operated) animals and SCI animals ( C ). BR, brush stimulation; PI, pinch stimulation using an arterial clip with a force of 250 g/mm2; PP, pinprick stimulation using a 25-g tungsten tip; VF, stimulation using a 4-g von Frey hair. * P < 0.01 versus that in sham-operated control animals. Data are shown as means ± SD.