Fig. 5. Effect of pretreatment of neutrophils with isoflurane (ISO) or sevoflurane (SEV) in the absence and presence of 8-phenyltheophylline (8-PT) on platelet-activating factor (PAF)–stimulated polymorphonuclear neutrophil (PMN) retention in isolated hearts ( A ) and on myeloperoxidase (MPO) activity in end-recovery hearts ( B ). Number in bar = number of hearts. Values are presented as mean ± SD. *P < 0.05 versus control group; # P < 0.05 versus corresponding anesthetics.