Fig. 3. Anesthesia of intact skin by 0.25% bupivacaine (0.6 ml). Normalized responses, shown as means ± SD, to a range of von Frey hairs measured at 0.5 cm from the injection site (  A ), 2 cm ipsilateral from injection site (  B ), and 2 cm contralateral from the injection site (  C ) (n = 4). von Frey hair forces were 18 (▪), 40 (○), 90 (▴), 150 (▿), and 520 mN (♦).