Fig. 5. Time course of graded secondary allodynia and hyperalgesia (as mean ± SD) measured at 2 cm ipsilateral (  A and  B ) and 2 cm contralateral (  C and  D ) from the site of the incision, after subcutaneous vehicle. The early changes in response are shown in  A and  C ; the changes over 1 week are shown in  B and  D . Significance cues and force-denoting symbols (*, #) are the same as in  figure 4 (n = 16).