Fig. 3. Expression of heme oxygenase 1 (HO-1) and heme oxygenase (HO) activity in the liver after pentobarbital (PENTO) or isoflurane (ISO) anesthesia, with or without dexamethasone (ISO + Dex), or gadolinium chloride (ISO + GdCl). ( A ) Northern blot. ( B ) Western blot. ( A and B ) The two lanes corresponding to each intervention show the results of two representative experiments. ( C ) Densitometric analysis of HO-1 messenger RNA (mRNA) and ( D ) HO activity of all individual experiments (n = 5–7/group). * P < 0.05 versus pentobarbital. # P < 0.05 versus isoflurane.