Fig. 4. Arterial blood concentration curves of lidocaine and prilocaine after peripheral nerve block with 20% (  A and  B ; four rats) or 60% (  C and  D ; six rats) lidocaine:prilocaine in lipid formulation.  Bold curves = population mean fit;  thin curves = disposition according to POSTHOC individual estimates;  dashed curves = predictions from  in vitro release profiles.