Fig. 4. Train-of-four tracing from one volunteer who participated during part 2 of the study. The  blue line represents the height of the twitch, and the  dashed red line is the value of the train-of-four ratio. The volunteer received 0.6 mg/kg rocuronium (Roc) followed by placebo at 3 min (  A ) in one treatment period, followed by 8 mg/kg Org 25969 in another treatment period (  B ). No recurarization was observed in the 90 min during which the neuromuscular block was monitored.