Fig. 3. Graph showing the plasma time course of prostaglandin E2(PGE2), interleukin 6 (IL-6), and interleukin 8 (IL-8) concentration in control hip surgery patients. Baseline value just before surgical incision (0 h value) were 446.4, 12.2, 0.0 pg·ml–1, respectively. Asterisks indicate significant difference ( P < 0.05) from baseline. Note: IL-6 values at 1 h and IL-8 values at 1 and 24 hours are below the detection limit.