Fig. 2. ( A ) Overlay of typical traces depicting the dose-dependent effects of propofol (1, 10, 100 μm) on intracellular free Ca2+concentration ([Ca2+]i) and shortening in an individual diabetic cardiomyocyte. ( B ) Summarized data for the effects of propofol on [Ca2+]iand shortening in diabetic ( filled bars ) and normal ( open bars ) cardiomyocytes. * P < 0.05 versus control (Ctrl). # P < 0.05 versus normal at the same concentration of propofol. n = 20 cells from five hearts (diabetic); n = 12 cells from four hearts (normal).