Fig. 1. Postischemic neurologic deficit of animals pretreated with erythromycin (25 mg/kg intramuscularly) 6, 12, or 24 h before the injury ( black squares , n = 27, pooled) or with vehicle only ( gray diamonds , n = 25, pooled). Erythromycin-pretreated animals had less neurologic deficit after global ischemia beyond the immediate postoperative recovery (days 4–7, P < 0.05). Data for sham-operated animals ( vertical bars , n = 6) are provided for comparison. Data shown are median and 25th/75th percentiles. * P < 0.05 versus vehicle-treated animals; rank sum test.