Fig. 1. Mean arterial blood pressure (MAP) and heart rate (HR) during infusion (0–10 min) and after termination of the infusion of lidocaine in groups C and E. Insets show MAP and HR during the whole experimental period. Data are expressed as mean ± SD of 10 experiments. * P < 0.05 compared with baseline within the study group. † P < 0.01 compared with group C at the same time point. bpm = beats/min.