Fig. 7. Typical population effect site concentration–response curves of approximate entropy (ApEn;  A ), 95% spectral edge frequency (SEF95;  B ), and canonical univariate parameter (CUP;  C ), modeled by nonlinear mixed effects modeling. 

Fig. 7. Typical population effect site concentration–response curves of approximate entropy (ApEn;  A ), 95% spectral edge frequency (SEF95;  B ), and canonical univariate parameter (CUP;  C ), modeled by nonlinear mixed effects modeling. 

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