Fig. 6. Influence of acute late sepsis or rocuronium on critical depolarization of muscle membrane. Critical depolarizations in the cecal ligation and puncture (CLP) group (  filled columns ) were significantly (  P < 0.05 or  P < 0.01) smaller than those in the sham group (  open columns ) at 0 (baseline), 5, and 15 μm rocuronium, but there was no significant difference between critical depolarization at 0 μm rocuronium (baseline) and that at 5 or 15 μm rocuronium in both the sham and CLP groups. *  P < 0.01  versus sham; **  P < 0.05  versus sham; n = 25 at 0 (baseline), 5 and 15 μm rocuronium, each.