Fig. 3. Hemodynamic effects. Group data show pulmonary artery pressure (PAP), arterial pressure (AP), aortic flow, and the ratio of pulmonary over systemic vascular resistance (PVR/SVR) before and after inhalation ( A and B ) or intravenous ( C ) delivery of milrinone ( filled circles ) or NaCl ( open circles ) in congestive heart failure (CHF) rats ( A and C ) or sham-operated animals ( B ), respectively. Concentrations for milrinone and NaCl aerosols were 1 mg/ml and 0.9%, respectively. Intravenous doses were 10-μg/kg body weight bolus and 1-μg · kg body weight−1· min−1infusion rate for milrinone and equal volumes for 0.9% NaCl. Data are from n = 11 rats in each group. * P < 0.05 versus baseline (before). # P < 0.05 versus NaCl.
