Fig. 4. Self-reported fatigue scores at 2 and 6 h after surgery, at 9 am, 1 pm, and 5 pm on the first day after surgery, and at 9 am and 1 pm on the second day after surgery. Fatigue was reported on a 100-mm visual analog scale (VAS), with 0 mm being no fatigue and 100 mm being the worst imaginable fatigue. *  P < 0.05 as compared with saline.