Fig. 6. Expression of Bax and Bcl-2 in the CA1 area of hippocampus in rats. Representative photomicrographs of the CA1 area of hippocampus illustrating Bax and Bcl-2 expression from a control (no-intervention) rat (  A ), or from rats receiving anesthesia alone tested at 1 (  B1 ), 3 (  B3 ), or 7 (  B7 ) days after anesthesia or animals tested 1 (  C1 ), 3 (  C3 ), or 7 (  C7 ) days after anesthesia and surgery. (  D ) Histogram plotting the number of Bax- and Bcl-2–positive cells in the cohorts undergoing anesthesia and surgery (mean ± SD; n = 6). **  P < 0.01  versus C7.