Figure 1. Effect of continuous intravenous administration of thiopental on delayed neuronal death of CA1 pyramidal cells. Thiopental was administered (A) immediately before the start of ischemia and (B) immediately after the end of ischemia. CA1 pyramidal cells were examined 7 days after the 3-min ischemia, and the percentage (the average of values on both sides) of degenerated pyramidal cells (ordinate) was determined. Values obtained from individual animals are shown. Data are not included for two animals in the postischemic group treated with 2 mg [centered dot] kg sup -1 [centered dot] min sup -1 thiopental for 60 min that died. *P < 0.01 compared with the values in the control group.