Figure 1. Changes in hepatic flow and oxygen consumption. Values are mean +/- SD. (A) Effects of isoflurane on the changes in basal hepatic flow and oxygen consumption. There were significant differences in basal oxygen consumption between the control group and the 2-minimum alveolar concentration (P = 0.04163) or 1-minimum alveolar concentration (P = 0.04742) isoflurane group (repeated-measures analysis of variance followed by contrast). (B) The effects of isoflurane on changes in hepatic flow and oxygen consumption during hypoxia-reoxygenation. Hypoxic challenge significantly altered the change in hepatic oxygen consumption (P <0.00001 by repeated-measures analysis of variance).