Fig. 2. Effects of PJ-34 on poly(adenosine diphosphate–ribose) polymerase (PARP) activity, inflammatory cell counts, and lung injury. (  A ) PARP activity (U/g protein) in lung homogenate after 4 h of ventilation. HTV = high tidal volume; LTV = low tidal volume. (  B ) Leukocyte cell counts in lung lavage after 4 h of ventilation. (  C ) Lung wet-to-dry weight ratio. (  D ) Lung injury score. *  P < 0.05, LTV + vehicle  versus LTV + PJ-34, and HTV + vehicle  versus HTV + PJ-34. †  P < 0.05, LTV + vehicle  versus HTV + vehicle. ‡  P < 0.05, HTV + vehicle  versus others. 

Fig. 2. Effects of PJ-34 on poly(adenosine diphosphate–ribose) polymerase (PARP) activity, inflammatory cell counts, and lung injury. (  A ) PARP activity (U/g protein) in lung homogenate after 4 h of ventilation. HTV = high tidal volume; LTV = low tidal volume. (  B ) Leukocyte cell counts in lung lavage after 4 h of ventilation. (  C ) Lung wet-to-dry weight ratio. (  D ) Lung injury score. *  P < 0.05, LTV + vehicle  versus LTV + PJ-34, and HTV + vehicle  versus HTV + PJ-34. †  P < 0.05, LTV + vehicle  versus HTV + vehicle. ‡  P < 0.05, HTV + vehicle  versus others. 

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