Fig. 1. Myotoxicity (MTox) from injection of 10% (wt/wt) bupivacaine microparticles (DAL). (  A ) Low-magnification view (100×) showing inflammation in the area of injection of the particles, between the sciatic nerve (SN) and muscle. (  B ) High-magnification view (200×) of severe perifascicular myotoxicity adjacent to the microparticles (which are not visible) in a separate animal. M = muscle.