Fig. 5.
Microvascular leakage and fluid resuscitation requirements. Evans blue dye extravasation in kidneys and lungs after hemorrhagic shock and fluid resuscitation (Resuscitation) with vasculotide treatment (Resuscitation+VT; A). Absolute amount of blood withdrawn and Ringer’s lactate solution and heparinized shed blood required for fluid resuscitation after hemorrhagic shock (B). Data represent mean ± SD. A, n = 8, one-way ANOVA with Bonferroni post hoc analyses; B, n = 15, Student t test. *P < 0.05, **P < 0.01, ***P < 0.001.