Fig. 3.
Results of study 1: Effect of GAL021 versus placebo on minute ventilation (A), tidal volume (B), and respiratory rate (C). B represents baseline (no drug, no added inspired carbon dioxide), C represents the carbon dioxide clamp before any drug infusion, P1 represents low-dose alfentanil (ALF) infusion before any GAL021 or placebo infusion (carbon dioxide-clamp plus ALF-low), P2 the combination of low-dose alfentanil and low-dose GAL021 or placebo (carbon dioxide-clamp plus ALF-low plus GAL021-low), P3 the combination of low-dose alfentanil with high-dose GAL021 or placebo (carbon dioxide-clamp plus ALF-low plus GAL021-high), and P4 the combination of high-dose alfentanil with high-dose GAL021 or placebo (carbon dioxide-clamp plus ALF-high plus GAL021-high). Values are mean ± 95% CI. *P < 0.01 versus placebo.