Figure 4. Glutathione (GSH) and glutathione disulfide (GSSG) concentrations in venous blood from the femoral vein of the leg ([diamond], local) before and after application of a pneumatic tourniquet for bloodless knee surgery and simultaneously from an antecubital vein of an arm ([diamond], systemic). Significance at P < 0.05;*versus preoperatively (Pre-OP);(double dagger)versus 0.5 min;(paragraph)versus 5 min;(dagger)versus 10 min;(section)versus systemic.