Figure 1. Time-course of changes of SVRI (median, range) from baseline (0 min) in 22 desflurane-treated ([round bullet, filled]) and 22 sevoflurane-treated ([circle, open]) patients. A significant difference in the time-course (slope analysis of curves) from 0 to 5 min was found. No difference between groups from 7 to 15 min was noted.