Figure 3. A, Simulated and measured [9,10] thiopental serum concentrations in humans after bolus injection. The inset displays the first 20 min. B, Simulated and measured [9,11] thiopental serum concentrations in humans after short infusions ranging from 2 to 12.4 min. The inset displays the first 20 min. C, Prediction error versus time for the bolus data. D, Prediction error versus time for the infusion data.