Fig. 5.
Simultaneous microdialysis in the left locus coeruleus (LC) and left lumbar spinal dorsal horn. After two 30-min baseline samples, vehicle (Veh) or capsaicin (Cap, 150 μg/50 μl) was injected into the left forepaw in normal and spinal nerve ligated (SNL) rats. Changes in glutamate (Glu, A) and noradrenaline (NA, B) concentrations in microdialysates from the LC and spinal cord are presented over the time as percentage of baseline. Data are presented as mean ± SD. Groups were analyzed by two-way repeated-measures ANOVA (Time × Group).