American Society of Anesthesiologists

Fig. 6.

Graph showing the dynamic uptake of 18F-labeled fluoroethoxybenzyl-N-(4-phenoxypyridin-3-yl) acetamide (18F-FEPPA) expressed as standard uptake value (SUV) versus time in a region of interest in the left temporal cortex from control, sevoflurane-treated, sevoflurane + acetyl-l-carnitine (ALC), and control + ALC monkeys (n = 4/group) 1 day (A), 7 days (B), and 21 days after exposure (C). Data are shown as the mean ± SEM. *P < 0.05, sevoflurane vs. control; ^P < 0.05, sevoflurane vs. control + ALC; #P < 0.05, sevoflurane vs. sevoflurane + ALC.

Graph showing the dynamic uptake of ¹⁸F-labeled fluoroethoxybenzyl-N-(4-phenoxypyridin-3-yl) acetamide (¹⁸F-FEPPA) expressed as standard uptake value (SUV) versus time in a region of interest in the left temporal cortex from control, sevoflurane-treated, sevoflurane + acetyl-l-carnitine (ALC), and control + ALC monkeys (n = 4/group) 1 day (A), 7 days (B), and 21 days after exposure (C). Data are shown as the mean ± SEM. *P < 0.05, sevoflurane vs. control; ^P < 0.05, sevoflurane vs. control + ALC; #P < 0.05, sevoflurane vs. sevoflurane + ALC.

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