Boxplots of anxiety behavior (e.g., scratch, shake) exhibited by infants exposed to isoflurane (ISO) 0 (control), 1 (ISO-1), or 3 (ISO-3) times during focal observations at 12 months of age. The middle line in the box represents the median, the box outline represents the interquartile range, bars represent the range, and the open circle represents the outlier. *P < 0.05.