![Figure 1. The biphasic vasorelaxant effect of 10 sup -10 to 3 [center dot] 10 sup -6 M D888 on 3 [center dot] 10 sup -7 M norepinephrine-contracted Nomega-nitro-L-arginine-pretreated rat aortic rings (n = 9). Hill analysis of the data yielded the following parameter values: The first segment of 10 sup -10 to 3 [center dot] 10 sup -7 M lead to 34.4 +/- 1.9% inhibition of initial tension at half-maximum effective concentration values of 8.09 = 1.40 nM.](https://asa2.silverchair-cdn.com/asa2/content_public/journal/anesthesiology/88/3/10.1097_00000542-199803000-00023/2/23ff1.png?Expires=1717072524&Signature=Fbf6DxBRXO5AZbbTKMQG8Z9voXiFQlliLpVx8sHajd~-CHbrNxGTrq6NfctvEkpupSS~InN1DyE79DEuQJkJAm59kPSoudAGFx-VwQJ1eyNi4gYeZKrjbFVCh8VMWjXN~SPsZT4xZ~JM0w~hVJ8MZPN4YU9YWBjOcgu~ovi-k-Uxz2oUhVmOCvXdFAWbWrRISsPX6DXE-SWrGXl9dTPlWvYqUMxDd1eK-YiIL4hKaE-ACjNeJnZ6zCnZHlUA1WXe64AKYOIZ1lTEaw-7oZzudtFTMjNDdLRXhNJ4vj3IcWEHIJlVyir1cTbfJjzYZQL~18Ek0jvgnxKkTFXgx1H1SA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Figure 1. The biphasic vasorelaxant effect of 10 sup -10 to 3 [center dot] 10 sup -6 M D888 on 3 [center dot] 10 sup -7 M norepinephrine-contracted Nomega-nitro-L-arginine-pretreated rat aortic rings (n = 9). Hill analysis of the data yielded the following parameter values: The first segment of 10 sup -10 to 3 [center dot] 10 sup -7 M lead to 34.4 +/- 1.9% inhibition of initial tension at half-maximum effective concentration values of 8.09 = 1.40 nM.
