Calculated absolute uptake and elimination of the volatile anesthetics. The uptake of isoflurane and desflurane (A and B; n =7) and elimination (C and D; n = 7) from arterial blood before and during methacholine nebulization at sample time points (mean ± SD). The data are displayed at the respective time in milliliters of anesthetic (vapor) per kilogram of body weight per minute. MCh = methacholine.