Fig. 2.
Burn shock hemodynamic pattern in the first 48 h. In the first hours, burn injury leads to initial low cardiac output (CO; A) and systemic and pulmonary vasoconstriction (B). Within 24 to 48 h, a hyperdynamic and vasoplegic state develops, which is characterized by a high CO (A) and decreased systemic and pulmonary vascular resistances (B). This pattern was observed with or without fluid resuscitation. Fluid resuscitation was, however, associated with a faster restoration of CO as well as higher CO during the hyperdynamic phase, especially when albumin is infused with crystalloids. Figure adapted from Asch et al.1