Figure 2. Mean (plus/minus SD; n = 10) stroke volumes in the four groups at baseline, 4 h postsepsis, and 6 h postsepsis. In group 1, SV was unchanged between conditions. In group 2 (hemofiltration [HF]) and group 4 (HF and phenylephrine [PE]), SV increased after treatment. In group 3, SV decreased when PE alone was instituted. *P < 0.05 versus 4 h and **P < 0.05 versus other conditions within a group by repeated-measures analysis of variance and Student-Newman-Keul analysis; +P < 0.05 versus groups 1 and 3 and (open circle)P < 0.05 versus other groups in which the respective changes in stroke volume between 4 and 6 h in the four groups are compared by one-way between-groups analysis of variance and Student-Newman-Keul analysis.