Figure 3. Mean (plus/minus SD; n = 10) cardiac outputs in the four groups at baseline, 4 h postsepsis, and 6 h postsepsis. HF = hemofiltration; PE = phenylephrine. *P < 0.05 from baseline and 4 h postsepsis by repeated-measures analysis of variance; +P < 0.05 versus groups 1 and 3 and (open circle)P < 0.05 versus other groups in which the respective changes in cardiac output observed between 4 and 6 h postsepsis in the four groups are compared by one-way between-groups analysis of variance and Student-Newman-Keul analysis.