Figure 2. Log dose-response curve for the effects of nociceptin on maximum paw withdrawal latency (top) and post-drug difference score (bottom). Maximum paw withdrawal latency is the single longest paw withdrawal latency during the experiment. A post-drug difference score is calculated by subtracting the maximum paw withdrawal latency of the control side (left side) from the maximum paw withdrawal latency of the injured side (right side). Each line represents the mean +/- SD of five or six rats. Injured paw = sciatic nerve injured paw (right paw); uninjured paw = sciatic nerve uninjured paw.