Figure 4. Values for V1estimated in NONMEM's post-hoc pharmacokinetic analysis are plotted against weight and age. The line, determined using a smoother (lowess), suggests that there is no relation between V1and either weight or age.

Figure 4. Values for V1estimated in NONMEM's post-hoc pharmacokinetic analysis are plotted against weight and age. The line, determined using a smoother (lowess), suggests that there is no relation between V1and either weight or age.

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