Figure 2. (A) Infarct size (mean +/- SD) expressed as a % of area at risk in rabbit hearts that were not pretreated (control, N = 13), exposed to 5 min of preconditioning (ischemic preconditioned, N = 8), or exposed to 15 min of 1.1% isoflurane (isoflurane, N = 15) before 30 min of anterolateral coronary occlusion. Symbols (#,*,+) indicate that statistical analysis showed that the relationship between infarct size and area at risk was different in each group (P < 0.05, see Table 1). (B) Relationship between infarct size and myocardium at risk for the three groups. Control ([horizontal bar], [round bullet, filled]) isoflurane (-----, [square, open]) preconditioned ([dotted line], [circle, open]). For regression equations and statistical analysis see Table 1. All three regression lines were statistically different because of differences in line elevation.