Figure 7. Effects of thiopental on the ATP-evoked current. (A) The current activated by rapid perfusion of ATP, 30 micro Meter, was measured in cell held at -60 mV before and after thiopental (right and left panel). Thiopental, 100 micro Meter, was applied with ATP after 5 min preperfusion (middle panel). (B) Summarized data for effects of thiopental on the ATP-evoked current. The current was measured as in (A) and normalized to the average of the control current before and after thiopental applications. In the control condition, relative current is the second response normalized to the average of the first and third responses during three successive ATP applications. Each column represents mean and SEM of four to five experiments. An asterisk indicates significant difference from the control by Dunnett's test for multiple comparison (*P < 0.05).

Figure 7. Effects of thiopental on the ATP-evoked current. (A) The current activated by rapid perfusion of ATP, 30 micro Meter, was measured in cell held at -60 mV before and after thiopental (right and left panel). Thiopental, 100 micro Meter, was applied with ATP after 5 min preperfusion (middle panel). (B) Summarized data for effects of thiopental on the ATP-evoked current. The current was measured as in (A) and normalized to the average of the control current before and after thiopental applications. In the control condition, relative current is the second response normalized to the average of the first and third responses during three successive ATP applications. Each column represents mean and SEM of four to five experiments. An asterisk indicates significant difference from the control by Dunnett's test for multiple comparison (*P < 0.05).

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