Fig. 1.
Estimation of BRS using the sequence method. Electrocardiogram and SAP waveforms are recorded simultaneously, and then beat-to-beat SAP and the calculated RRIs are plotted against time course. (A) SAP and RRI signals and the baroreflex sequences acquired using the sequence method. Blue squares indicate up sequences. Red circles indicate down sequences. Sequence selection criteria were as follows: SAP greater than 0.5 mmHg; RRI greater than 1 ms; sequence greater than 3; and a significant correlation coefficient (r > 0.9). Note that the significant sequences cluster in segments where SAP and RRI signals apparently oscillate more coherently (in this case, at the start and the end of this recording). (B) Within-subject variability of the BRS. Mean up, down, and overall BRS were calculated from the sequences shown in A. BRS, baroreceptor sensitivity; RRI, R–R intervals; SAP, systolic arterial pressure.

Estimation of BRS using the sequence method. Electrocardiogram and SAP waveforms are recorded simultaneously, and then beat-to-beat SAP and the calculated RRIs are plotted against time course. (A) SAP and RRI signals and the baroreflex sequences acquired using the sequence method. Blue squares indicate up sequences. Red circles indicate down sequences. Sequence selection criteria were as follows: SAP greater than 0.5 mmHg; RRI greater than 1 ms; sequence greater than 3; and a significant correlation coefficient (r > 0.9). Note that the significant sequences cluster in segments where SAP and RRI signals apparently oscillate more coherently (in this case, at the start and the end of this recording). (B) Within-subject variability of the BRS. Mean up, down, and overall BRS were calculated from the sequences shown in A. BRS, baroreceptor sensitivity; RRI, R–R intervals; SAP, systolic arterial pressure.

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