Fig. 5.
Graph A depicts the relationship between the remifentanil effect site concentration (Ce) and the fractional decrease in baseline ventilation () measured (1-min average) at end-infusion. Linear regression analysis did not reveal any systematic bias of the obstructive sleep apnea (OSA) subjects (i.e., for both study groups, the slope of the regression line was not different than 0). Graph B shows the significant linear relationship between the cumulative dose of remifentanil and total body weight in OSA and control participants, separately. Comparison of the regression slopes did not reveal any statistically significant difference between the two groups (P = 0.222).