Figure 2. Effect of cholesterol on pentobarbital-induced sodium channel suppression. (A) Current traces as in Figure 1A, except in the presence of 680 micro Meter pentobarbital (same channels as in Figure 1A). (B) Time-averaged current through the same channels as in Figure 1C, after addition of 680 micro Meter pentobarbital; curves were significantly different (slope conductances are 13.7 plus/minus 0.2, 17.4 plus/minus 0.3, and 20.9 plus/minus 0.2 pS, respectively).